Hello,
another suggestion for functionality that might be extremely helpful in real applications that require high sensitivity.
Imagine that, for any reason, I have a precomputed Fulgor index (k=31), but need to go to lower k's (eg k=20, which would still be reasonably high for Fulgor to work ok-ish – even if speed is partially downgraded).
Would it be possible to somehow easily generate an updated 20-mer index from the original 31-mer index? I assume that the core issue is likely the SPSS recomputation but there might be tricks how to (partially) avoid this.
(Eg, for applications such as Phylign, this would be a killer feature – we would distribute indexes for a high k, and the end user could tailor them for their use case.)
Thanks
Karel
Hello,
another suggestion for functionality that might be extremely helpful in real applications that require high sensitivity.
Imagine that, for any reason, I have a precomputed Fulgor index (k=31), but need to go to lower k's (eg k=20, which would still be reasonably high for Fulgor to work ok-ish – even if speed is partially downgraded).
Would it be possible to somehow easily generate an updated 20-mer index from the original 31-mer index? I assume that the core issue is likely the SPSS recomputation but there might be tricks how to (partially) avoid this.
(Eg, for applications such as Phylign, this would be a killer feature – we would distribute indexes for a high k, and the end user could tailor them for their use case.)
Thanks
Karel