MoltenProt

MoltenProt is a graphical and command-line application for fitting protein thermal unfolding data. For more details see the publication:

In-depth interrogation of protein thermal unfolding data with MoltenProt

https://doi.org/10.1002/pro.3986

Installation

Pre-packaged binaries

See Releases to get ready-to-use executables for Windows and Mac.

Older versions of MoltenProt are also available here:

http://marlovitslab.org/lab/Download.html

From source code

If you have python (versions 3.8 and above) available on your system, you can install MoltenProt as follows:

1. (OPTIONAL) create a virtual environment:

   python -m venv venv

2. (OPTIONAL) activate the virtual environment:

   a. Windows:

   venv\Scripts\activate

   b. GNU/Linux and Mac:

   source venv/bin/activate

3. Install the MoltenProt package from this repo:

   python -m pip install --use-pep517 moltenprot[gui,multiproc]@git+https://github.com/kvr2007/moltenprot.git@master

   (this will install with GUI and multiprocessing capability)

   alternatively, download a WHL file from releases and run:

   python -m pip install moltenprot-0.4.1b0-py3-none-any.whl[gui,multiproc]

   (the actual file name may differ depending on the version)

You can now launch the GUI with command moltenprot_gui or access the CLI with moltenprot.

For additional documentation see INSTALL.

CHANGELOG

To test the installation run:

python -m moltenprot.test

Usage

User guide is available in PDF format and also from the GUI "Help > MoltenProt help".

Survey

If you regularly use MoltenProt, please consider filling out the usage survey:

MoltenProt Survey

No sensitive data is collected in the survey, and it will help prioritize future developments.

Getting help

Please open an issue here.