The eigenWeightedMean is a pretty hand single-sample score, however its score can be driving by outliers with high expression.
We can try calculating gene weights in the same way we do in eigenWeightedMean, but produce a score that is eigen-weighted average of the gene z-scores.
The
eigenWeightedMeanis a pretty hand single-sample score, however its score can be driving by outliers with high expression.We can try calculating gene weights in the same way we do in
eigenWeightedMean, but produce a score that is eigen-weighted average of the gene z-scores.