microsoft · anupriya13 · Jul 22, 2025 · Jul 17, 2025 · Jul 17, 2025 · Jul 18, 2025
diff --git a/change/@office-iss-react-native-win32-98074e3b-7f24-4400-a7e4-daca6e150710.json b/change/@office-iss-react-native-win32-98074e3b-7f24-4400-a7e4-daca6e150710.json
@@ -0,0 +1,7 @@
+{
+  "type": "prerelease",
+  "comment": "Integrate RN Nightly Build 0.80.0-nightly-20250506-3ac16dd6a",
+  "packageName": "@office-iss/react-native-win32",
+  "email": "54227869+anupriya13@users.noreply.github.com",
+  "dependentChangeType": "patch"
+}
diff --git a/change/@react-native-windows-automation-channel-f520c795-6a39-4d20-a6a9-487784b06176.json b/change/@react-native-windows-automation-channel-f520c795-6a39-4d20-a6a9-487784b06176.json
@@ -0,0 +1,7 @@
+{
+  "type": "patch",
+  "comment": "Integrate RN Nightly Build 0.80.0-nightly-20250506-3ac16dd6a",
+  "packageName": "@react-native-windows/automation-channel",
+  "email": "54227869+anupriya13@users.noreply.github.com",
+  "dependentChangeType": "patch"
+}
diff --git a/change/react-native-windows-0b31b288-b7cb-48e2-945e-3d032942ea6c.json b/change/react-native-windows-0b31b288-b7cb-48e2-945e-3d032942ea6c.json
@@ -0,0 +1,7 @@
+{
+  "type": "prerelease",
+  "comment": "Integrate RN Nightly Build 0.80.0-nightly-20250506-3ac16dd6a",
+  "packageName": "react-native-windows",
+  "email": "54227869+anupriya13@users.noreply.github.com",
+  "dependentChangeType": "patch"
+}
diff --git a/packages/@office-iss/react-native-win32-tester/overrides.json b/packages/@office-iss/react-native-win32-tester/overrides.json
@@ -5,7 +5,7 @@
   "excludePatterns": [
     "src/js/examples-win32/**"
   ],
-  "baseVersion": "0.80.0-nightly-20250428-9efcdc091",
+  "baseVersion": "0.80.0-nightly-20250506-3ac16dd6a",
   "overrides": [
     {
       "type": "patch",
@@ -42,7 +42,7 @@
       "type": "derived",
       "file": "src/js/utils/RNTesterList.win32.js",
       "baseFile": "packages/rn-tester/js/utils/RNTesterList.android.js",
-      "baseHash": "3b5c8bcdee69293ddce0d515300504979e36f87a"
+      "baseHash": "aded9dd37f3ac325aa1cc095f6d217114c45a8b9"
     }
   ]
 }
diff --git a/packages/@office-iss/react-native-win32-tester/package.json b/packages/@office-iss/react-native-win32-tester/package.json
@@ -19,7 +19,7 @@
   "peerDependencies": {
     "@office-iss/react-native-win32": "^0.0.0-canary.293",
     "react": "19.1.0",
-    "react-native": "0.80.0-nightly-20250428-9efcdc091"
+    "react-native": "0.80.0-nightly-20250506-3ac16dd6a"
   },
   "devDependencies": {
     "@office-iss/react-native-win32": "^0.0.0-canary.293",
@@ -30,7 +30,7 @@
     "@types/node": "^18.0.0",
     "eslint": "^8.19.0",
     "just-scripts": "^1.3.3",
-    "react-native": "0.80.0-nightly-20250428-9efcdc091",
+    "react-native": "0.80.0-nightly-20250506-3ac16dd6a",
     "react-native-platform-override": "^1.9.56",
     "typescript": "5.0.4"
   },

diff --git a/.../@office-iss/react-native-win32-tester/src/js/examples-win32/Theming/ThemingModuleAPI.tsx b/.../@office-iss/react-native-win32-tester/src/js/examples-win32/Theming/ThemingModuleAPI.tsx
@@ -24,13 +24,13 @@ const styles = StyleSheet.create({
 
 const Theming = NativeModules.Theming;
 
-const ifModuleAvailable = (wrappedComponent: React.JSX.Element) => {
+const ifModuleAvailable = (wrappedComponent: React.ReactElement): React.ReactElement => {
   return Theming ? wrappedComponent : <Text>Theming Native Module not available</Text>;
 };
 
-const RenderThemeFunction = () => {
+const RenderThemeFunction = (): React.ReactElement => {
   const [, setText] = React.useState('');
-  const onChangeText = React.useCallback(t => setText(t), [setText]);
+  const onChangeText = React.useCallback((t: string) => setText(t), [setText]);
   return (
     <View style={styles.nestedContainer}>
       <Text>Arguments: </Text>
@@ -39,68 +39,85 @@ const RenderThemeFunction = () => {
   );
 };
 
-const ThemingMethods: React.FunctionComponent<{}> = () => {
+const withBox = (
+  key: string,
+  component: React.ReactElement | React.ReactElement[]
+): React.ReactElement => (
+  <View style={styles.box} key={key}>
+    <Text style={styles.header}>{key}</Text>
+    <>{component}</>
+  </View>
+);
+
+const ThemingMethods: React.FunctionComponent = () => {
   return (
     <View>
-      {Object.keys(Theming).map((val: string) => {
-        return typeof Theming[val] === 'function' ? withBox(val, RenderThemeFunction()) : undefined;
-      })}
+      <>
+        {Object.keys(Theming).map((val: string) =>
+          typeof Theming[val] === 'function' ? withBox(val, <RenderThemeFunction />) : null
+        )}
+      </>
     </View>
   );
 };
 
-const renderNestedObject = (obj: Record<string, any>) => {
+const renderNestedObject = (obj: Record<string, any>): React.ReactElement => {
   return (
     <View style={styles.nestedContainer}>
       <ScrollView>
-        {Object.keys(obj).map((val: string) => {
-          return <Text key={val}>{val + ': ' + JSON.stringify(obj[val])}</Text>;
-        })}
+        {Object.keys(obj).map((val: string) => (
+          <Text key={val}>{val + ': ' + JSON.stringify(obj[val])}</Text>
+        ))}
       </ScrollView>
     </View>
   );
 };
 
-const renderObject = (obj: Record<string, any>) => {
+const renderObject = (obj: Record<string, any>): React.ReactElement => {
   const firstKey = Object.keys(obj)[0];
   const formattedOutput = JSON.stringify(obj)
     .replace(/],/g, '],\n\n')
     .replace(/:/g, ': ')
     .replace(/,/g, ', ');
-  return obj[firstKey] instanceof Array ? <Text style={styles.nestedContainer}>{formattedOutput}</Text> : renderNestedObject(obj);
-};
 
-const renderThemeObject = (key: string): React.ReactElement => withBox(key, renderObject(Theming[key]));
+  return obj[firstKey] instanceof Array ? (
+    <Text style={styles.nestedContainer}>{formattedOutput}</Text>
+  ) : (
+    renderNestedObject(obj)
+  );
+};
 
-const withBox = (key: string, component: React.ReactNode) => (
-  <View style={styles.box} key={key}>
-    <Text style={styles.header}>{key}</Text>
-    {component}
-  </View>
-);
+const renderThemeObject = (key: string): React.ReactElement =>
+  withBox(key, renderObject(Theming[key]));
 
-const ThemingConstants: React.FunctionComponent<{}> = () => {
+const ThemingConstants: React.FunctionComponent = () => {
   return (
     <View>
-      {Object.keys(Theming).map((val: string) => {
-        return typeof Theming[val] === 'object' ? renderThemeObject(val) : undefined;
-      })}
+      <>
+        {Object.keys(Theming).map((val: string) =>
+          typeof Theming[val] === 'object' ? renderThemeObject(val) : null
+        )}
+      </>
     </View>
   );
 };
 
 export const title = 'Theming Module APIs';
 export const displayName =  'Theming Module APIs';
 export const description = 'Tests shape of Theming Native Module';
-export const examples = [
-    {
-      title: 'Theming Module Constants',
-      description: 'All constants',
-      render: () => ifModuleAvailable(<ThemingConstants />),
-    },
-    {
-      title: 'Theming Module Methods',
-      description: 'Method invoker',
-      render: () => ifModuleAvailable(<ThemingMethods />),
-    },
-  ];
+export const examples: {
+  title: string;
+  description: string;
+  render: () => React.ReactElement;
+}[] = [
+  {
+    title: 'Theming Module Constants',
+    description: 'All constants',
+    render: (): React.ReactElement => ifModuleAvailable(<ThemingConstants />),
+  },
+  {
+    title: 'Theming Module Methods',
+    description: 'Method invoker',
+    render: (): React.ReactElement => ifModuleAvailable(<ThemingMethods />),
+  },
+];
diff --git a/packages/@office-iss/react-native-win32-tester/src/js/utils/RNTesterList.win32.js b/packages/@office-iss/react-native-win32-tester/src/js/utils/RNTesterList.win32.js
@@ -233,14 +233,6 @@ const APIs: Array<RNTesterModuleInfo> = ([
       .default,
   },
   // Only show the link for the example if the API is available.
-  // $FlowExpectedError[cannot-resolve-name]
-  typeof IntersectionObserver === 'function'
-    ? {
-        key: 'IntersectionObserver',
-        category: 'UI',
-        module: require('../examples/IntersectionObserver/IntersectionObserverIndex'),
-      }
-    : null,
   {
     key: 'InvalidPropsExample',
     module: require('../examples/InvalidProps/InvalidPropsExample'),
@@ -265,14 +257,6 @@ const APIs: Array<RNTesterModuleInfo> = ([
     category: 'UI',
     module: require('../examples/Layout/LayoutExample'),
   },
-  // $FlowExpectedError[cannot-resolve-name]
-  typeof MutationObserver === 'function'
-    ? {
-        key: 'MutationObserver',
-        category: 'UI',
-        module: require('../examples/MutationObserver/MutationObserverIndex'),
-      }
-    : null,
   {
     key: 'NativeAnimationsExample',
     category: 'UI',
@@ -380,11 +364,6 @@ const APIs: Array<RNTesterModuleInfo> = ([
     category: 'Basic',
     module: require('../examples/TurboModule/TurboCxxModuleExample'),
   },
-  {
-    key: 'PerformanceApiExample',
-    category: 'Basic',
-    module: require('../examples/Performance/PerformanceApiExample'),
-  },
 ]: Array<?RNTesterModuleInfo>).filter(Boolean);
 
 if (ReactNativeFeatureFlags.shouldEmitW3CPointerEvents()) {

diff --git a/packages/@office-iss/react-native-win32/.flowconfig b/packages/@office-iss/react-native-win32/.flowconfig
@@ -5,6 +5,9 @@
 .*/*[.]macos.js
 .*/*[.]windesktop.js
 
+; Ignore fb_internal modules
+<PROJECT_ROOT>/packages/react-native/src/fb_internal/.*
+
 ; These modules have base components and win32 versions.
 ; Ideally we'd delete the base versions of files that had .win32 overrides as part of the
 ; initRNLibraries build step
@@ -39,6 +42,10 @@
 <PROJECT_ROOT>/Libraries/LogBox/UI/LogBoxInspectorReactFrames.js
 <PROJECT_ROOT>/Libraries/LogBox/UI/LogBoxStyle.js
 
+<PROJECT_ROOT>/IntegrationTests/ImageCachePolicyTest.js
+<PROJECT_ROOT>/IntegrationTests/LayoutEventsTest.js
+<PROJECT_ROOT>/IntegrationTests/IntegrationTestsApp.js
+
 ; Ignore react-native files in node_modules since they are copied into project root
 .*/node_modules/react-native/.*
 
@@ -167,4 +174,4 @@ untyped-import
 untyped-type-import
 
 [version]
-^0.268.0
+^0.269.1
diff --git a/packages/@office-iss/react-native-win32/overrides.json b/packages/@office-iss/react-native-win32/overrides.json
@@ -7,13 +7,13 @@
     "**/__snapshots__/**",
     "src-win/rntypes/**"
   ],
-  "baseVersion": "0.80.0-nightly-20250428-9efcdc091",
+  "baseVersion": "0.80.0-nightly-20250506-3ac16dd6a",
   "overrides": [
     {
       "type": "derived",
       "file": ".flowconfig",
       "baseFile": ".flowconfig",
-      "baseHash": "d274ca7bb384b334c5b2ee0827726e7a3d6c98c9"
+      "baseHash": "70ed729d5f52c241530e8459cc40263d4e9fa9c0"
     },
     {
       "type": "derived",
@@ -114,7 +114,7 @@
       "type": "derived",
       "file": "src-win/Libraries/Components/TextInput/TextInput.win32.js",
       "baseFile": "packages/react-native/Libraries/Components/TextInput/TextInput.js",
-      "baseHash": "4b3128471dd0d362e9828df8937f708d53694e12"
+      "baseHash": "9965c0079652083ab549bc2799eb9528b56a1b2d"
     },
     {
       "type": "patch",
@@ -183,13 +183,13 @@
       "type": "derived",
       "file": "src-win/Libraries/Components/View/ViewAccessibility.d.ts",
       "baseFile": "packages/react-native/Libraries/Components/View/ViewAccessibility.d.ts",
-      "baseHash": "d97e29f01e57cc2b0de209a03f8584b984cfe190"
+      "baseHash": "1e4e3a89397960e8f08b86be62496473829c0ac3"
     },
     {
       "type": "derived",
       "file": "src-win/Libraries/Components/View/ViewAccessibility.win32.js",
       "baseFile": "packages/react-native/Libraries/Components/View/ViewAccessibility.js",
-      "baseHash": "c30dab3926869e84edafebd485e78637d69ccd61"
+      "baseHash": "04981261b2ed61b31bfbb396478bb6b103d99253"
     },
     {
       "type": "derived",
@@ -329,7 +329,7 @@
       "type": "derived",
       "file": "src-win/Libraries/NativeComponent/BaseViewConfig.win32.js",
       "baseFile": "packages/react-native/Libraries/NativeComponent/BaseViewConfig.ios.js",
-      "baseHash": "3ba8fe1a60d744e057e856bc43e2df28f4fd7f66"
+      "baseHash": "b520e2bdb2be31bdb6ad7e3769dbe69168870c8c"
     },
     {
       "type": "copy",

diff --git a/packages/@office-iss/react-native-win32/package.json b/packages/@office-iss/react-native-win32/package.json
@@ -30,19 +30,19 @@
     "@react-native-community/cli-platform-android": "17.0.0",
     "@react-native-community/cli-platform-ios": "17.0.0",
     "@react-native/assets": "1.0.0",
-    "@react-native/assets-registry": "0.80.0-nightly-20250428-9efcdc091",
-    "@react-native/codegen": "0.80.0-nightly-20250428-9efcdc091",
-    "@react-native/community-cli-plugin": "0.80.0-nightly-20250428-9efcdc091",
-    "@react-native/gradle-plugin": "0.80.0-nightly-20250428-9efcdc091",
-    "@react-native/js-polyfills": "0.80.0-nightly-20250428-9efcdc091",
-    "@react-native/normalize-colors": "0.80.0-nightly-20250428-9efcdc091",
-    "@react-native/virtualized-lists": "0.80.0-nightly-20250428-9efcdc091",
+    "@react-native/assets-registry": "0.80.0-nightly-20250506-3ac16dd6a",
+    "@react-native/codegen": "0.80.0-nightly-20250506-3ac16dd6a",
+    "@react-native/community-cli-plugin": "0.80.0-nightly-20250506-3ac16dd6a",
+    "@react-native/gradle-plugin": "0.80.0-nightly-20250506-3ac16dd6a",
+    "@react-native/js-polyfills": "0.80.0-nightly-20250506-3ac16dd6a",
+    "@react-native/normalize-colors": "0.80.0-nightly-20250506-3ac16dd6a",
+    "@react-native/virtualized-lists": "0.80.0-nightly-20250506-3ac16dd6a",
     "abort-controller": "^3.0.0",
     "anser": "^1.4.9",
     "ansi-regex": "^5.0.0",
     "art": "^0.10.0",
     "babel-jest": "^29.7.0",
-    "babel-plugin-syntax-hermes-parser": "0.25.1",
+    "babel-plugin-syntax-hermes-parser": "0.28.1",
     "base64-js": "^1.5.1",
     "chalk": "^4.0.0",
     "commander": "^12.0.0",
@@ -52,8 +52,8 @@
     "invariant": "^2.2.4",
     "jest-environment-node": "^29.7.0",
     "memoize-one": "^5.0.0",
-    "metro-runtime": "^0.82.0",
-    "metro-source-map": "^0.82.0",
+    "metro-runtime": "^0.82.2",
+    "metro-source-map": "^0.82.2",
     "mkdirp": "^0.5.1",
     "nullthrows": "^1.1.1",
     "pretty-format": "^29.7.0",
@@ -62,7 +62,7 @@
     "react-devtools-core": "^6.1.1",
     "react-refresh": "^0.14.0",
     "regenerator-runtime": "^0.13.2",
-    "scheduler": "0.25.0",
+    "scheduler": "0.26.0",
     "semver": "^7.1.3",
     "stacktrace-parser": "^0.1.10",
     "whatwg-fetch": "^3.0.0",
@@ -72,7 +72,7 @@
   "devDependencies": {
     "@babel/core": "^7.25.2",
     "@babel/eslint-parser": "^7.25.1",
-    "@react-native/metro-config": "0.80.0-nightly-20250428-9efcdc091",
+    "@react-native/metro-config": "0.80.0-nightly-20250506-3ac16dd6a",
     "@rnw-scripts/babel-react-native-config": "0.0.0",
     "@rnw-scripts/eslint-config": "1.2.36",
     "@rnw-scripts/jest-out-of-tree-snapshot-resolver": "^1.1.40",
@@ -88,14 +88,14 @@
     "just-scripts": "^1.3.3",
     "prettier": "2.8.8",
     "react": "19.1.0",
-    "react-native": "0.80.0-nightly-20250428-9efcdc091",
+    "react-native": "0.80.0-nightly-20250506-3ac16dd6a",
     "react-native-platform-override": "^1.9.56",
     "typescript": "5.0.4"
   },
   "peerDependencies": {
-    "@types/react": "^19.0.0",
+    "@types/react": "^19.1.0",
     "react": "^19.1.0",
-    "react-native": "0.80.0-nightly-20250428-9efcdc091"
+    "react-native": "0.80.0-nightly-20250506-3ac16dd6a"
   },
   "beachball": {
     "defaultNpmTag": "canary",