Please see the reproducing test case here: https://github.com/shlomif/node-js-bug--debug-gets-stuck-on-two-c-commands namely doing:
shlomif@telaviv1:~/node-js-debug-gets-stuck-on-two-c$ /home/shlomif/apps/node-js/bin/node debug perlito5.js -I src5/lib -I MyDir/lib -I MyDir/lib/expand-solitaire-multi-card-moves
< Debugger listening on port 5858
connecting to 127.0.0.1:5858 ... ok
break in perlito5.js:20
18 // See http://www.perl.com/perl/misc/Artistic.html
19
>20 "use strict";
21 var isNode = typeof require != "undefined";
22
debug> c
debug> c
Causes the debugger to hang without being able to interrupt using either ctrl+c or ctrl+z. I'm using node-v5.4.0 on Mageia Linux x86-64 v6. More info can be found in the link.