-
Notifications
You must be signed in to change notification settings - Fork 0
Closed
Labels
new-featureNew functionality being added.New functionality being added.
Description
- Container for omega
- Omega preprocessing module
- Omega running module
- Create sample/gene/consequence grouping JSON.
- OmegaGlobalLoc #87
// SUBWORKFLOW: omega
// Description:
// - Compute positive selection based on mutation recurrence.
// Input:
// - Depths
// - Mutations
// - Mutation profile
// - Regions to focus the analysis annotated (pending to update omega version with this working)
// - Sample gene and consequence groups. (set defaults: all samples independent, all samples together
// all genes independent, all genes together,
// all genes in the analysis that are known cancer genes,
// set default consequence types
// )
// Output:
// - omega results
// - Plots ?
// Modules:
// - Intersect regions bedfile with depths
// - Intersect the intersection of the previous two files with the mutations
// - Omega preprocessing module
// - Omega estimator module
// - Plot results:
// Ideas:
// Clustermap of all individual samples
// Sanger-like, with number of mutations per type with all samples, and then positive selection for each of the impacts
// Positive selection per each of the genes.
Reactions are currently unavailable
Metadata
Metadata
Assignees
Labels
new-featureNew functionality being added.New functionality being added.